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Hudson College Launches New Center to Address Health Concerns in Young Children

Hudson College Launches New Center to Address Health Concerns in Young Children


Published: Thursday, July 24, 2025

University of Oklahoma researchers from the Hudson College of Public Health launched the Children’s Environmental Health Center in the U.S. Southern Great Plains, a groundbreaking initiative dedicated to advancing research on children’s health and environmental exposures, following a year of preparation. Funded by a $1.8 million grant from the U.S. Environmental Protection Agency, this new center aims to reduce school absences by addressing the health impacts affecting children in rural and agricultural communities across the Southern Great Plains. The research will also inform the development of effective and affordable interventions to improve health outcomes for children.

“Our team is working to understand how early-life exposure to both chemical and non-chemical stressors affect children’s health and well-being in these communities,” said Changjie Cai, Ph.D., Assistant Professor in the Department of Occupational and Environmental Health at the Hudson College of Public Health and a leader on the project. “The goal of the center is to better serve the Southern Great Plains region, with a focus on mitigating early-life stage exposures that span from prenatal development through early childhood to adolescence, particularly in rural agricultural communities.”

This collaborative center is led by Cai, who serves as its director and is the principal investigator for the research effort. The team includes Diane Horm, Ph.D., a professor emeritus and the founding director of the OU-Tulsa Childhood Education Institute, and Dan Li, Ph.D., an associate professor in the OU Department of Health Promotion Sciences.

The center builds on the ongoing OK-AIR project (Advancing Indoor-environment Research for Children in Oklahoma), which is led by Horm, and will continue and expand upon its work. The OK-AIR project is originally funded by the Oklahoma Partnership for School Readiness and the Preschool Development Grant.

Research has shown that children in rural and agricultural communities face increased health risks due to environmental exposures. These risks stem from pollutants in the air, water and soil and extreme weather, as well as socioeconomic stressors such as poverty and limited access to health care. The center aims to reduce school absenteeism by addressing these key environmental and social factors. “This progress is the result of strong school-family-community partnerships and the implementation of a comprehensive, tiered approach,” Li said.

“At the Early Childhood Education Institute, our mission has always been to support the well-being of young children through research,” Horm said. “This collaboration will allow us to better assess and address the factors influencing children’s health in rural areas.”

The center will also develop a community-driven and data-driven Children’s Health and Social Vulnerability Index at both the community level and individual level to assess health and social needs in rural programs. This index will identify both chemical and non-chemical stressors associated with school absenteeism and will guide comprehensive, tiered interventions aimed at improving children’s health, educational outcomes and overall well-being in these communities.

Pictured is Cai sharing with the crowd. Photo by Andrew Craig.

    

Conference Presentations

  • More to expect soon
  • Cai, C., & Horm, D. (2025). OK-AIR: Advancing Indoor-environment Research for Children in Oklahoma. Annual Regional Conference: Building Healthy Futures: Policies, Partnerships, and Pathways for Child Wellbeing, organized by American Mock World Health Organization, Oklahoma City, OK 73104, USA, November 8.
  • Horm, D., & Cai, C. (2025). OK-AIR: Advancing Indoor-environment Research for Children in Oklahoma. UMC El Paso’s 4th Annual Nursing Research & Quality Symposium, El Paso, TX, USA, October 24.
  • Cai, C., & Horm, D. (2025). OK-AIR: Advancing Indoor-environment Research for Children in Oklahoma. Region VI Head Start Association Southwestern Fall Conference, Dallas, TX, USA, October 23.
  • Cai, C., & Horm, D. (2025). Aerosol Hazards and Health: Understanding and Control in Public Health & Early Childhood Settings. Southern Plains Tribal Health Board (SPTHB) Virtual Training Summit, OK, USA, August 12.
  • Horm, D., & Cai, C. (2025). OK-AIR: Advancing Indoor-environment Research for Children in Oklahoma. For Kelley Smith from EPA Region 6, IAQ in Schools, Zoom, USA, July 31.
  • Horm, D., & Cai, C. (2025). OK-AIR: Advancing Indoor-environment Research for Children in Oklahoma. Children’s Environmental Health Symposium, Oklahoma City, OK 73104, USA, June 25-26.
  • Horm, D., & Cai, C. (2025). Air Quality Intervention in Head Start Classrooms. Kickoff and Network Event for the Children’s Environmental Health Center in the U.S. Southern Great Plains, Oklahoma City, OK 73104, USA, April 4.
  • Horm, D., & Cai, C. (2024). OK-AIR: Advancing Indoor-environment Research for Children in Oklahoma. 2024 Oklahoma Early Childhood Research Symposium, Oklahoma City, OK 73179, USA, September 23-24.
  • Cai, C., & Horm, D. (2024). OK-AIR: Advancing Indoor-environment Research for Children in Oklahoma. Native Renewable Energy Symposium, University of Oklahoma, Norman, Oklahoma, USA, September 12-13.
  • Zhu, M., Kim, P., Akanji, B., Horm, D., Fuhrman, B., Sadhasivam, B., Stroh, O., Thomas, G., Peters, T., & Cai, C.* (2024). Characterize and Intervene the Indoor Air Quality in Early Childhood Education Settings to Reduce the School Absenteeism Caused by Infectious Diseases. Poster presentation at the Indoor Air 2024 Sustaining the Indoor Air Revolution: Raise Your Impact, Honolulu, Hawai‘i, July 7-11.
  • Horm, D., Craig, V. P., Cai, C., Fuhrman, B., Dericks, A., Farris, S., Ssentuuwa, R., Ghorbani, E., Zhu, M., Akanji., B., & Kim, P. (2024). Indoor Air Quality: A Literature Review and RCT Study in Early Head Start/Head Start. Poster presentation at the National Research Conference on Early Childhood 2024 (NRCEC 2024), Arlington, VA. June 24-26.
  • Zhu, M., Akanji, B., Horm, D., Fuhrman, B., Sadhasivam, B., Stroh, O., Thomas, G., Peters, T., Xu, C., & Cai, C.* (2024). Evaluating Interventions for Indoor Air Quality and Teachers’ Absenteeism in Winter: A Randomized Controlled Experiment in Early Childhood Education Centers. Poster presentation at the American Industrial Hygiene Connect 2024 (AIHA Connect 2024), Columbus, OH. May 20-22.
  • Cai, C., Horm, D., & Li, D. (2024). Children’s Environmental Health Center in U.S. Southern Great Plains. 2024 Cumulative Impacts Research Grantee Workshop, Environmental Protection Agency (EPA), North Carolina, USA, May 14-16.
  • Joseph, M., & Cai, C.* (2024). Particle Deposition in 3D Printed Human Lung Model Under Realistic Physiological Conditions. Poster presentation at the Honors College FYRE Poster Symposium, Norman, OK. May 1. 

Publications

  • More to expect soon
  • Cai, C., Horm, D., Fuhrman, B., Van Pay, C. K., Zhu, M., Shelton, K., ... & Xu, C. (2026). OK-AIR study protocol: a longitudinal cluster-randomised 2× 2 factorial trial of portable air purification and upper-room UVGI on sick-related absences, indoor air quality, environmental pathogens and social-emotional development in early care and education classrooms (birth-5 years). medRxiv, 2026-03.
  • Liu, S., Yang, A., Horm, D., Zhu, M., & Cai, C. (2026). Developing an Early Childhood Environmental Health Vulnerability Index to Assess Cumulative Health Impacts Across Contiguous US. medRxiv, 2026-03.

Clinic Study Registry

  • OK-AIR: Testing classroom air cleaners and upper-room UV air treatment to improve indoor air quality and reduce sick-related absences in Oklahoma early care and education (ECE) schools, ISRCTN: ISRCTN78764448. DOI https://doi.org/10.1186/ISRCTN78764448